Issue link: https://www.ascpskindeepdigital.com/i/1539961
Protection. Education. Connection. There's an app for that at ascpskincare.com/app 49 INGREDIENT DECK • Provides comparable wound-healing and barrier-restoring properties • Offers sustainable, vegan friendly, and cruelty-free alternatives In the treatment room, professionals might prefer botanical PDRN because it: • Eliminates seafood allergy concerns • Has broader client acceptance and comfort levels • Uses sustainable sourcing that appeals to environmentally conscious practices • Has enhanced formulation stability in some applications EVIDENCE-BASED EFFICACY: SETTING EXPECTATIONS As professionals, it's essential to maintain realistic expectations about PDRN's effi cacy across diff erent delivery methods, especially since estheticians cannot administer injectables. Evidence shows the following: Injectable PDRN (Strongest Evidence) • Clinical trials supporting regenerative benefits • Direct dermal delivery ensures optimal bioavailability • Proven efficacy for acne scarring, texture improvement, and signs of aging • Established guidelines for protocols and dosing Topical PDRN (Emerging Evidence) • Limited clinical studies compared to injectable forms • Molecular-size barriers may affect penetration and efficacy • Most beneficial for barrier support and postprocedure healing • Enhanced delivery through microneedling or professional protocols In the treatment room, topical PDRN shines as an ideal adjunct to support barrier recovery and boost postprocedure healing, especially after treatments like chemical peels or microneedling. It's a gentle yet eff ective way to calm, hydrate, and encourage regeneration and it could be considered as a maintenance step between appointments. Helping clients understand the benefi ts and limitations of topical PDRN—including how its delivery method aff ects results—sets realistic expectations, builds trust, and reinforces your role as a credible, results-driven professional. Industry Insights and Product Selection The professional PDRN market has expanded signifi cantly, with several key players off ering practitioner-grade formulations. Available Product Categories • Professional-grade serums and ampoules for in-clinic use • Take-home maintenance products for client protocols • Sheet masks and intensive treatments for postprocedure care • Combination formulations with complementary actives Notable Professional Lines • Rejuran Professional: fi ve-piece regimen formulated for topical use under US regulations • VT Cosmetics: botanical PDRN formulations • Various Korean professional brands: range of concentrations and delivery systems Ingredient Identifi cation • INCI names: Sodium DNA, Plant DNA Extract, Panax Ginseng Root Extract, specifi c botanical extracts • Look for molecular weight specifi cations (50–1,500 kDa range) • Concentration levels are 0.1–2 percent in professional formulations