INGREDIENT DECK
available compound and offers superior safety
in skin care formulations, so it could be the next
big ingredient for the management of a variety
of skin conditions.
• Naringin—This is also a bioflavonoid with
free radical scavenging and anti-inflammatory
properties. Because of its ability to inhibit the
substances that produce reactive oxygen species, it
is incredibly effective in stopping and preventing
damage caused by UVB radiation. Topical
applications of naringin can prevent both sun- and
age-induced elasticity reduction. When combined
in a skin care formulation with hesperidin, naringin
has shown remarkable wound contracting and
collagen remodeling for deep, dermal injuries.
FIND YOUR MAIN SQUEEZE
There are many citrus fruit compounds that
contribute to providing a "grapefruit state of mind"
for the skin. Whether carefully incorporated into
skin care formulations or included as part of a
balanced diet, citrus can provide antioxidant, anti-
infl ammatory, and skin-balancing benefi ts. Extracts
can deliver a pleasant, natural scent from fl avonoids,
or terpenes, which also bring skin benefi ts. They
can encourage natural exfoliation, signal skin
brightening, and even stimulate scar revision. Citrus
fruit extracts can provide the skin with fortifi cation
to fi ght against degeneration caused by the sun and
other environmental factors and are even natural
alternatives for formulation preservatives and
emulsifi ers. This citrus season, it's a fi tting time to
celebrate the many dermal benefi ts found in our
citrus friends.
Resources
Al-Niami, F., and N. Y. Z. Chiang. "Topical Vitamin C and the Skin:
Mechanisms of Action and Clinical Applications." Journal of Clinical and
Aesthetic Dermatology 10, no. 7 (July 2017): 14–7. ncbi.nlm.nih.gov/pmc/
articles/PMC5605218.
Carpenter, K. J. "The Discovery of Vitamin C." Annals of Nutrition
and Metabolism 61, no. 3 (2012): 259–64. karger.com/anm/article-
abstract/61/3/259/40403/The-Discovery-of-Vitamin-C.
Green, B., E. Bernstein, and B. Edison. "Citric Acid: An Alpha and
Beta Hydroxyacid for Antiaging." Journal of the American Academy
of Dermatology 52, no. 3, (March 2005): 87. researchgate.net/
publication/298404874_Citric_acid_ An_alpha_and_beta_hydroxyacid_
for_antiaging.
Grzybowski, A., and K. Pietrzak. "Albert Szent-Györgyi (1893-1986): The
Scientist Who Discovered Vitamin C." Clinics in Dermatology 31, no. 3
(May–June 2013): 327–31. pubmed.ncbi.nlm.nih.gov/23738385.
Hou, M., et al. "Topical Hesperidin Improves Epidermal Permeability
Barrier Function and Epidermal Di erentiation in Normal Murine Skin."
Experimental Dermatology 21, no. 5 (May 2012) 337–40. onlinelibrary.wiley.
com/doi/10.1111/j.1600-0625.2012.01455.x.
Lim, K. H., and G. R. Kim. "Inhibitory E ect of Naringenin on LPS-Induced
Skin Senescence by SIRT1 Regulation in HDFs." Biomedical Dermatology 2,
no. 26 (2018). biomeddermatol.biomedcentral.com/articles/10.1186/s41702-
018-0035-6.
Man, M-Q., B. Yang, and P. M. Elias. "Benefi ts of Hesperidin for
Cutaneous Functions." Evidence-Based Complementary and Alternative
Medicine (April 2019). hindawi.com/journals/ecam/2019/2676307.
Ren, X., et al. "Naringin Protects Ultraviolet B-Induced Skin Damage by
Regulating p38 MAPK Signal Pathway." Journal of Dermatological Science
82, no. 2 (May 2016): 106–14. jdsjournal.com/article/S0923-1811(15)30091-
8/fulltext.
Vabeiryureilai, M., K. Lalrinzuali, and G. C. Jagetia. "NF-KB and COX-2
Repression with Topical Application of Hesperidin and Naringin Hydrogels
Augments Repair and Regeneration of Deep Dermal Wounds." Burns 48,
no. 1 (February 2022): 132–45. Sciencedirect.com/science/article/abs/pii/
S0305417921000978.
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