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of growth factors stimulated
by microneedling, which
in turn revitalizes collagen
and elastin production. The
procedure is safe, comfortable,
and compliant with most
state regulations on depth of
penetration within the skin.
A SYMPHONY
OF TREATMENTS
Achieving optimal results necessitates
a well-orchestrated symphony of
treatments. The pretreatment phase
focuses on exfoliation, brightening
ingredients, and restoring skin health;
imagine facials, enzymes, peels,
microexfoliation, and microinfusion
working in harmony to prepare your
client's skin for the advanced modalities
to come. Exfoliation should be performed
2–4 weeks before microneedling to ensure
optimal results. Meanwhile, professional
home care featuring mandelic acid
and vitamin C sets the stage for
pretreatment and posttreatment care.
After microneedling, adhering to a proper
posttreatment routine is paramount.
This includes avoiding prolonged sun
exposure, embracing professional
home care products, and applying
broad-spectrum sunscreen daily. Light
chemical peels performed two weeks
postmicroneedling can yield incredible
results in lifting out stubborn pigment.
Remember, a series of treatments is
the key to unlocking the full potential
of your client's skin transformation
Edison, B. L. et al. "18295 Mandelic
Acid, a Lipophilic Alpha Hydroxy Acid,
Reduces Lipid Production, Enhances
Exfoliation and Provides Clinical and
Patient Perceivable Benefits to Oily
and Photodamaged Skin." Journal of the
American Academy of Dermatology 83,
no. 6 (December 2020). jaad.org/article/
S0190-9622(20)31574-7/abstract.
Farris, P. K. "Topical Vitamin C: A
Useful Agent for Treating Photoaging
and Other Dermatologic Conditions."
Dermatologic Surgery 31, no. S1 (July
2005): 814–8. onlinelibrary.wiley.
com/doi/abs/10.1111/j.1524-4725.2005.31725.
Guo, J. et al. "A Novel Multi-Fruit Acids Formula
Design on Molecular Basis for Skin Brightening via
a System Biology Approach." Journal of Cosmetic
Dermatology 21, no. 11 (November 2022): 6145–55.
Onlinelibrary.wiley.com/doi/abs/10.1111/jocd.15163.
Jacobs, S. W. and E. J. Culbertson. "Effects
of Topical Mandelic Acid Treatment on Facial
Skin Viscoelasticity." Facial Plastic Surgery 34,
no. 6 (2018). thieme-connect.com/products/
ejournals/abstract/10.1055/s-0038-1676048.
Majeed, S., N. Mahmood, and S. Ahmed.
"Comparative Efficacy of Topical 4% Hydroquinone
vs. 4% Hydroquinone Plus 10% Mandelic Acid in the
Treatment of Melasma." Journal of Pakistan Association
of Dermatologists 28, no. 3 (July–September 2018).
jpad.com.pk/index.php/jpad/article/view/1265.
Sanadi, R. M. and R. S. Deshmukh. "The Effect of
Vitamin C on Melanin Pigmentation—A Systematic
Review." Journal of Oral and Maxillofacial Pathology
24, no. 2 (May–August 2020). journals.lww.com/jpat/
fulltext/2020/24020/%20The_ E%EF%AC%80ect_of_
Vitamin_C _on_ Melanin_ Pigmentation.32.aspxAge.
Sharon, M. et al. Mandelic Acid. Bloomington:
Partridge Publishing India, 2018.
TRANSFORM YOUR CLIENT'S SKIN
In the quest for radiant skin, the
harmonious marriage of effective
ingredients that enhance exfoliation,
inhibit tyrosinase, and reduce
inflammation and the advanced
modalities that stimulate collagen
production and regulate melanogenesis
is of utmost importance. By unraveling
the complex mechanisms at play and
harnessing the powers of science, you
can unlock a comprehensive solution for
achieving the balanced and even skin
tone your clients have always desired.
Resources
Dębowska, R. M. et al. "Evaluation of the Efficacy
and Tolerability of Mandelic Acid-Containing
Cosmetic Formulations for Acne Skin Care."
Dermatology Review 102 (April 2015): 316–21.
termedia.pl/Evaluation-of-the-efficacy-and-
tolerability-of-mandelic-acid-containing-cosmetic-
formulations-for-acne-skin-care,56,25608,1,1.html.
Dormael, R. D. "Vitamin C Prevents Ultraviolet-
Induced Pigmentation in Healthy Volunteers:
Bayesian Meta-Analysis Results from 31
Randomized Controlled Versus Vehicle Clinical
Studies." Journal of Clinical and Aesthetic
Dermatology 12, no. 2 (February 2019): E53–9.
Ncbi.nlm.nih.gov/pmc/articles/PMC6415704.
The secret lies in the
release of growth
factors stimulated by
microneedling, which in
turn revitalizes collagen
and elastin production.
