Issue link: https://www.ascpskindeepdigital.com/i/1489006
New member benefit! Get the ASCP SkinPro app at ascpskincare.com/skinpro 37 INGREDIENT DECK CONSIDERATIONS As with all ingredients or new products, it is important to be aware of potential contraindications. Generally, copper peptide is considered a low-risk component. However, using high concentrations has been shown to possibly cause in ammation and irritation. Borrowing a standard from Goldilocks, e ective product formulations should not include too little or too much—you want a copper peptide concentration that is "just right." Copper peptides don't necessarily play well with others. Care should be taken when using strong hydroxy acids, retinoids, and high concentrations of potent antioxidants, since these well-intended ingredients can ght against each other. Though this poses minimal risk for reaction, it does mean the intended product e ect can be negated, which can challenge the entire skin care routine. AN INGREDIENT TO WATCH Copper peptides can be very e ective in the ght against skin issues. Proper formulations that include complementary ingredients provide stabilized delivery with cellular communication. It takes a village of compounds to ensure strong, healthy, youthful- behaving skin. When your clients ask about copper peptides, explain how they can work to positively a ect skin, and how they can work against even the best intentions. Finally, explain that as their trusted skin care expert, you will help guide them through exactly what they need to use to reach their skin care goals. Notes 1. Loren Pickart, "The Human Tri-Peptide GHK and Tissue Remodeling," Journal of Biomaterials Science, Polymer Edition 19, no. 8 (2008): 969–88, https://pubmed.ncbi.nlm.nih.gov/18644225. 2. Giana Angelo, Oregon State University, "Peptides and Skin Health," 2012, https://lpi.oregonstate.edu/mic/health-disease/skin-health/peptides. 3. Loren Pickart and Anna Margolina, "Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data," International Journal of Molecular Sciences 19, no. 7 (1987): www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405. 4. Alain Siméon et al., "The Tripeptide-Copper Complex Glycyl- L-Histidyl-L-Lysine-Cu2+ Stimulates Matrix Metalloproteinase-2 Expression by Fibroblast Cultures," Life Sciences, 67, no. 18 (2000): 2,257–65, https://pubmed.ncbi.nlm.nih.gov/11045606. GHK-Cu copper peptide powder.